JPH0441144B2 - - Google Patents

Info

Publication number
JPH0441144B2
JPH0441144B2 JP58217069A JP21706983A JPH0441144B2 JP H0441144 B2 JPH0441144 B2 JP H0441144B2 JP 58217069 A JP58217069 A JP 58217069A JP 21706983 A JP21706983 A JP 21706983A JP H0441144 B2 JPH0441144 B2 JP H0441144B2
Authority
JP
Japan
Prior art keywords
group
amino
dimethoxy
carbon atoms
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58217069A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59106466A (ja
Inventor
Raifuen Manfuretsudo
Haidaa Yohahimu
Ausuteru Fuorukuharuto
Haueru Noruberuto
Kobingaa Barutaa
Ririi Kurisuchan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS59106466A publication Critical patent/JPS59106466A/ja
Publication of JPH0441144B2 publication Critical patent/JPH0441144B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Luminescent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
JP58217069A 1982-11-18 1983-11-17 ベンゾアゼピン化合物 Granted JPS59106466A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823242599 DE3242599A1 (de) 1982-11-18 1982-11-18 Neue benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE32425996 1982-11-18

Publications (2)

Publication Number Publication Date
JPS59106466A JPS59106466A (ja) 1984-06-20
JPH0441144B2 true JPH0441144B2 (en]) 1992-07-07

Family

ID=6178417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58217069A Granted JPS59106466A (ja) 1982-11-18 1983-11-17 ベンゾアゼピン化合物

Country Status (23)

Country Link
EP (1) EP0109636B1 (en])
JP (1) JPS59106466A (en])
KR (1) KR840006628A (en])
AT (1) ATE40118T1 (en])
AU (1) AU568101B2 (en])
CA (1) CA1211107A (en])
CS (1) CS239947B2 (en])
DD (1) DD215540A5 (en])
DE (2) DE3242599A1 (en])
DK (1) DK527483A (en])
ES (2) ES8502424A1 (en])
FI (1) FI834174A7 (en])
GB (1) GB2130213B (en])
GR (1) GR81253B (en])
HU (1) HU193189B (en])
IE (1) IE56261B1 (en])
IL (1) IL70258A (en])
NO (1) NO834222L (en])
NZ (1) NZ206305A (en])
PL (1) PL139449B1 (en])
PT (1) PT77683B (en])
YU (1) YU226283A (en])
ZA (1) ZA838572B (en])

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3418271A1 (de) * 1984-05-17 1985-11-21 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3631013A1 (de) * 1986-09-12 1988-03-24 Thomae Gmbh Dr K Neue naphthylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
JP2699511B2 (ja) * 1988-01-29 1998-01-19 武田薬品工業株式会社 置換アミン類
FR2868776B1 (fr) * 2004-04-13 2008-04-18 Servier Lab Nouveau procede de synthese de derives de la 1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474090A (en) * 1966-12-22 1969-10-21 American Cyanamid Co 3-aminoalkyl-1,3-benzodiazepin-2-ones
US3780023A (en) * 1972-06-30 1973-12-18 J Suh 2-aralkylamino-4,5-dihydro-3h-1,3-benzodiazepines
US4210749A (en) * 1974-11-12 1980-07-01 Pennwalt Corporation Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines
DE2639718C2 (de) * 1976-09-03 1987-03-05 Dr. Karl Thomae Gmbh, 7950 Biberach 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
IN156096B (en]) * 1981-03-19 1985-05-11 Usv Pharma Corp
DE3119874A1 (de) * 1981-05-19 1982-12-09 Dr. Karl Thomae Gmbh, 7950 Biberach "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
EP0072352B1 (de) * 1981-08-11 1986-03-05 Ciba-Geigy Ag Benzazepin-2-one, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese Verbindungen enthalten, sowie die Verbindungen zur therapeutischen Verwendung
JPS6436829A (en) * 1987-07-31 1989-02-07 Shinko Kinzoku Kogyo Kk Evacuation part washing apparatus

Also Published As

Publication number Publication date
AU568101B2 (en) 1987-12-17
DK527483D0 (da) 1983-11-17
ES532662A0 (es) 1985-01-16
JPS59106466A (ja) 1984-06-20
IE832692L (en) 1984-05-18
GB2130213A (en) 1984-05-31
PT77683A (de) 1983-12-01
IL70258A (en) 1987-08-31
YU226283A (en) 1986-04-30
EP0109636A3 (en) 1985-11-21
IL70258A0 (en) 1984-02-29
ES527308A0 (es) 1985-01-01
ES8502424A1 (es) 1985-01-01
CA1211107A (en) 1986-09-09
DD215540A5 (de) 1984-11-14
FI834174A7 (fi) 1984-05-19
GR81253B (en]) 1984-12-11
ATE40118T1 (de) 1989-02-15
IE56261B1 (en) 1991-06-05
DK527483A (da) 1984-05-19
CS239947B2 (en) 1986-01-16
NO834222L (no) 1984-05-21
ZA838572B (en) 1985-07-31
FI834174A0 (fi) 1983-11-15
PL139449B1 (en) 1987-01-31
AU2146183A (en) 1984-05-24
GB8330731D0 (en) 1983-12-29
DE3378980D1 (en) 1989-02-23
PT77683B (de) 1986-05-12
EP0109636B1 (de) 1989-01-18
ES8502689A1 (es) 1985-01-16
PL244610A1 (en) 1985-07-16
HU193189B (en) 1987-08-28
NZ206305A (en) 1986-10-08
EP0109636A2 (de) 1984-05-30
GB2130213B (en) 1986-03-26
DE3242599A1 (de) 1984-05-24
KR840006628A (ko) 1984-12-01

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